Symbol
Name
ID

Akt1
thymoma viral proto-oncogene 1
MGI:87986

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Exocrine pancreatic insufficiency	Pancreatic adenocarcinoma	Goiter	Thyroid adenoma	Thyroiditis	Hyperthyroidism	Hypothyroidism
Disease(s) Associated with AKT1	Diabetes mellitus	Exocrine pancreatic insufficiency	Pancreatic adenocarcinoma	Goiter	Thyroid adenoma	Thyroiditis	Hyperthyroidism	Hypothyroidism
Cowden syndrome 6
pancreatic cancer

Mouse Phenotypes

abnormal sublingual gland morphology

abnormal palatine gland morphology

biliary cyst

dilated bile duct

abnormal thymus morphology

abnormal mammary gland duct morphology

mammary gland alveolar hyperplasia

abnormal mammary gland stroma morphology

mammary gland hyperplasia

abnormal testis morphology

small seminiferous tubules

seminiferous tubule degeneration

Availability

Mouse Genotype

Akt1^tm1Nhy/Akt1^tm1Nhy

Akt1^tm1.1Mjl/Akt1⁺

Tg(KRT5-Akt1*)Jmpa/0

Akt1^tm1Mjl/Akt1⁺
Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor^{tm1(cre/ERT)Nat} (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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